Phenibut HCL – Powder, 50 grams

The water-soluble GABA derivative phenibut HCl (β-phenyl-γ-aminobutyric acid hydrochloride) has a hydrochloride salt modification that improves stability and dissolution in aqueous solutions. Compared to natural GABA, it has a phenyl ring substitution that enhances lipophilicity and receptor binding. This substance mainly affects signal transduction and neurotransmitter regulation by interacting with GABA_B receptors. Renal clearance is the main excretion route for phenibut HCl, which is metabolized by the liver by conjugation and deamination. The hydrochloride form affects absorption kinetics and bioavailability because it is more soluble than its free amino acid equivalent.